Definitely we cannot help here because that is pure WebRTC API and browser vendor dependant implementation/behavior. If it does not work as expected, report to the browser vendor. mediasoup-client just honours the given options.
You can observe the effective RtpSender's RTP parameters by using:
To clarify: we don’t want this to be a generic WebRTC forum not to be a forum about Chrome issues/limitations when it comes to something purely related to the WebRTC spec.